TACTICAL PLANNING OF THREE-LEVEL SUPPLY CHAIN CONSIDERING SANCTION DISRUPTION AND SHELF LIFE: A CASE STUDY OF ATRA DRUG SUPPLY CHAIN

Tactical Planning of Three-Level Supply Chain considering Sanction Disruption and Shelf Life: A case Study of ATRA Drug Supply Chain

In the last two decades due to globalization of supply chain, enormous changes occurred in chains.Leaders in this field, always facing new risks and disorders that should prepare themselves to deal with them.In the recent years, sanctions as one of the most serious risks have damaged the supply chains.However, in the research related to global supp

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Physiologic medium renders human iPSC-derived macrophages permissive for M. tuberculosis by rewiring organelle function and metabolism

ABSTRACT In vitro studies are crucial for our understanding of the human macrophage immune functions.However, traditional in vitro culture media poorly reflect the metabolic composition of blood, potentially affecting the outcomes of these studies.Here, we analyzed the impact of a physiological medium on human induced pluripotent stem cell (iPSC)-d

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Separation of Binding Protein of Celangulin V from the Midgut of Mythimna separata Walker by Affinity Chromatography

Celangulin V, an insecticidal compound isolated from the root bark of Chinese bittersweet, can affect the digestive system of insects.However, the mechanism of how Celangulin V induces a series of symptoms is still unknown.In this study, affinity chromatography was conducted through coupling of Celangulin V-6-aminoacetic acid ester to the CNBr-acti

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